Elizabeth Holmes, founder and chief executive officer of now-defunct blood testing company Theranos, is exploring the idea of using “mental disease or defect” as part of her defense during her criminal fraud trial, which is set to begin in March after several delays.

Holmes is calling into question her mental faculties during the time period in which she allegedly engaged in criminal behavior as CEO of Theranos—but she would prefer the prosecution be denied the opportunity to evaluate that claim for themselves.

Aly McDevitt is Data & Research Journalist at Compliance Week. She has a background in education and college consulting. Prior to teaching, she was an editor/author at Thomson Reuters, where she reported...